Ubwino wa akupanga emulsization wokhazikika mu zodzikongoletsera ndi mankhwala

Ndikulimbanabe ndi mafuta omwe amalekanitsa mwachangu kuposa miseche yamaudindo ndi misala yaying'ono yomwe imasanduka zilumba zamafuta pansi?

Ngati "emussions yosakhazikika" imamveka ngati mutu wanu watsiku ndi tsiku mu labu, simuli nokha - ma crystalluze, kapena kutaya mawonekedwe ake ndi nthawi yodzikuza, ndi bajeti.

Mawu oyamba amayendamo momwe akupanga emulsization amathandizira pa Ultra - chabwino, emulsions okhazikika omwe amasunga madongosolo anu, zonena zanu qa zotsutsana ndi Qa.

Kuchokera pakuchepetsa tinthu tating'onoting'ono tomwe timakulitsa bioaavailabics, muwona chifukwa cha zodzikongoletsera komanso zamankhwala zimasinthana ndi chikhalidwe cha homogenization mpaka kumtunda - Akupanga Mapulogalamu.

Kwa iwo omwe amafunikira mawerengero ovuta, zomwe zimasanthula zaposachedwa zimapereka deta mwatsatanetsatane, kufananitsa kwa Roi, ndi mitundu yotengera msika:Akupanga kukonza lipoti la msika.

Kunyamula khofi; Emulsion yanu yokhazikika ikhoza kuyamba apa.

💧 Kuwongolera kwa Dropled Kuphulika kwa Crousent kwa nthawi yayitali - zodzikongoletsera zosakhalitsa ndi ma prermaceush

Akupanga emulsization amagwiritsa ntchito - Frequency Cavitation kuti mupange madontho abwinobwino kwambiri komanso ofowoka kwambiri, omwe amakomera kwambiri emulsion bata, zotupa, zotupa ndi kuyimitsidwa. Kugawa kwa Droplet yosasinthika, kutalika kwa gawo ndi kuwopa, kukulitsa moyo wa alumali komanso kusamalira ntchito zopanga kuti agwiritse ntchito.

Kuwongolera koyenera kumeneku ndikofunikira mu zodzoladzola za mbiri yosawoneka bwino komanso mu mankhwala ofanana. Ndi ma akupanga Makina, a proclaturers amathanso kufafaniza magawo monga matalikidwe, nthawi ndi mphamvu kuti akwaniritse kukula kwa chandamale kuchokera ku Micron kupita ku Nno Speale zotsatira zokhala ndi zolipiritsa.

1. Makina a akupanga cavitation kuti mupange mawonekedwe abwino emulsion

Nthawi yakupanga emulsization, kusinthana - ndi otsika - mafunde amakakamizidwa amapanga ma microbububle omwe amakula mwachangu ndikugwa. Cavitation iyi imatulutsa ubweya wamtundu wambiri ndi microjets yomwe imaswa bwino matomita ambiri m'magawo ang'onoang'ono.

• Kumeta ubweya wambiri mpaka masauzande a S⁻¹ pafupi ndi sonotrode
• Kusokonekera kosintha kwa droplomerates ndi masango
• Mapangidwe a kukula kwa masitepe (polydisperper)
• Kukonzanso mopitirira muyeso ndi zowonjezera, kukulitsa chidaliro cha kinetic

2. Ubwino wokhazikika kwa zonona, a seramu ndi emulsions

Madontho abwino ndi ofanana omwe amapezeka ndi ultrasound anawonjezera kukhazikika kwa mafuta onse - mu - Madzi ndi Madzi - mu - mu - Mafuta a Mafuta. Madontho ang'onoang'ono achepetsedwa kuchepetsedwa stoctation ndi midzi, ndipo malo ochulukirapo amathandiza anthu kupanga mafilimu ogona.

• Kuchepetsa chiopsezo cholekanitsidwa pa nthawi yosungirako ndi kutumiza
• Chizolowezi chotsika kuti apange mapangidwe a mafuta kapena matope
• Kusasinthika kwa mafakisoni ndi maonekedwe a alumali moyo
• Kuchita zolosera zambiri pansi pamayeso oyenda pamatumba

3..

Zodzikongoletsera zodzikongoletsera zimadalira akupanga emulsization kuti mukonze mawonekedwe, kufalikira ndi mawonekedwe. Madontho othamanga amapanga khungu labwino kwambiri kuti amveke pang'ono komanso kuyamwa mwachangu, ngakhale kufananako kumawasintha ngati kutopa komanso kulowerera.

4. Makina owongolera ndi kubereka m'mafakitale olamulidwa

Mu mankhwala opangira mankhwala ndi zamankhwala - zodzikongoletsera za grade, njira zolimba ndizofunikira. Makina akupanga amalola kusintha kwa mphamvu, pafupipafupi komanso kukonza nthawi yothandizira kubereka kwa kubereka, kuthandizira kuvomerezedwa ndi kuwongolera kovomerezeka.

• Magawo ogwiritsira ntchito njira zogwirira ntchito (Sps)
• Stable stococols kuchokera ku benchi kupita ku woyendetsa ndege kuti apangidwe kwathunthu
• Zowonjezera - to - Kusasinthika Kwambiri mumitundu yovuta
• Kugwirizana ndi - Zida Zowunikira Tinthu

🧴 Kukhazikika Bioavailability Bioavailabilialiality kudzera mwa ma nanoenully

Akupanga emulsization kumapangitsa kupanga kwa nanoemussions-emulsions ndi magwero a droplet, nthawi zambiri amakhala ndi mwayi wokulitsa bioaavailability wosasunthika. Malo akulu akulu ndi kukula kwa kalosi kumalimbikitsa kusinthika bwino, mayamwidwe ndi kulowa kunja kwa khungu, mucosal kapena m'mimba kapena m'mimba.

Izi nanoemusts zimathandizira kumasulidwa, ndikusungidwa bwino ndikutchinjiriza kwa zosakaniza ndi mavitamini, ma peptic, mankhwala a bovolilic, potengera lipophilic.

1. Momwe Nodo - Madontho Otsatsa Amalimbikitsa Kutengera Kuwala ndi Kulowa

Nanoemulsions amapereka gawo lalikulu kwambiri pamlingo uliwonse, womwe umathamangitsa kufalikira ndikuwonjezera kulumikizana ndi ziphuphu. Kukula pang'ono kwa kapoki kumathandizanso kuyanjana kwambiri ndi ma lipids akhungu kapena mucosal malo, owonjezera okhazikika komanso kukweza.

• Kuwongolera kusungunuka kwa Hydrophobic Apis (yogwira mafashoni)
• Kutulutsa kwa dermal komanso kutumiza kosinthanitsa mu cosmetic seramu
• Bwino bioavailability pamlomo wa lipid - Makina Osiyanasiyana a Mankhwala
• Kuchepetsa mlingo popanda kunyalanyaza

2. Kuteteza mamolekyulu owoneka bwino kuchokera kuwonongeka

Kuyika magwiridwe antchito mwakuwongolera madontho kumawateteza ku kuwala, oxygen ndi hydrolysis. Mafuta osanjikiza ndi surtictictures amapereka microenmentments yomwe imachepetsa kuwonongeka ndikupitirira ma molekyulu osakhazikika.

• Kukhazikika kwa mavitamini (a, c, e) ndi antioxidants
• Kutetezedwa ndi ma peptides, ma enzyme ndi a botanical akupanga
• Kuchepetsa kuchepetsedwa kwa ntchito nthawi yosungirako komanso kugawa
• Ntchito yodalirika kwambiri - ashel - Zinthu Zogulitsa Moyo

3. Kuzindikira kwa data: Kukula kwa Droplet vs. wachibale bioavailability

Ubale pakati pa kukula kwa masamba ndi bioavailability kumatha kufanizidwa ndi zoyeserera zoyeserera zofanizira poyerekeza ndi emulsions a emulsions and akupanga nanomalsions apisic apisic apisic apisic apisic apisic apisic apisic apisic apisic apisic apisic apisic apisic apisic apisic apisic API. Madontho ang'onoang'ono amakhala mogwirizana mogwirizana ndi chikondi chapamwamba bioavailabiliwobility, kuchirikiza kugwiritsa ntchito moyenera kugwiritsa ntchito ma ultrasound pakupanga mawonekedwe.

4. Mapulogalamu mu dermal, ma transdermalmal ndi njira zowonjezera pakamwa

Akupanga nanoemelsions amagwiritsidwa ntchito kwambiri pamsewu wowonjezera komanso mwatsatanetsatane. Mu chisamaliro cha khungu, iwo amathandizira kulowererapo kwa anti - kukalamba, kowala ndi anti - othandizira. Pazigawo za mankhwala, amagwirizana ndi zowonjezera pakamwa komanso zitha kukhala zopangidwa kuti zikapangidwe.

🧪 Akupanga kukonza zochepetsera Surfacticture ndi zilembo zotsuka

Akupanga emulsization akhoza kutsitsa kwambiri chidwi chofuna kukhazikika chifukwa cha Cavitation chimapereka magetsi obalalika ndi malo okwera. Forcelators imatha kukhalabe ndi kukhazikika ndi ma emulsifiers ochepa ndi coulsifiers ochepa komanso ogwiritsa ntchito, othandizira "zonena" zodzinenera kuti zimakwiyitsa kapena kusangalatsa.

Njira iyi imapindula ndi zodzoladzola komanso zowoneka bwino zamankhwala, kuphatikiza ndi oyang'anira komanso ogula zofuna zochepa, chabwino - zotsalira.

1. Makina opanga ochepetsa

Chifukwa ultrasound mwachangu amapanga madontho abwino ndipo amalimbikitsa madontho osafunikira a surmictice pa mawonekedwe a mafuta, mochepera emsilsifeer amafunikira kukhazikika pakubalalika kwa gawo lomwazika. Magetsi amagwiritsa ntchito kuchepetsedwa kwa kuchepetsedwa kwakanthawi popanga madontho ang'onoang'ono omwe amakhala ocheperako.

• Kusungunuka kwabwino koyenera kumachepetsa kufunikira kwa kuchuluka kwa zochulukirapo
• Kupititsa patsogolo kufalitsidwa kwa emulsiferier ku mawonekedwe
• Kuthekera kusinthira ma emulsifiers okhala ndi njira zina
• Chiopsezo chotsika chofananira ndi mkulu - Shear yosakanikirana

2.

Pazinthu zotsirizira zinthu zachilengedwe kapena hypoallergenic, zotsitsa zochepetsetsa zopepuka sizimasintha mindandanda ya ma eki ndipo amatumiza ndalama zowongolera. Akupanga emulsization amathandizira kunena kuti "otsika - kukwiya,"

• Mindandanda yocheperako yopanda zowonjezera zowonjezera
• Kugwirizanitsa bwino ndi okhazikika ndi achilengedwe
• Ochepetsedwa kufunika kwa mikangano kapena oletsedwa sofu
• Kudalira kwa ogula ndi mtundu

3. Mtengo wotsika ndi magwiridwe antchito mu mafakitale

Ourfacttonts ndi CO - Okhazikika nthawi zambiri amakhala pakati pa zokolola zodula kwambiri m'malo okwera. Pogwiritsa ntchito ma ultrasound kudula magawo, opanga amatha kuchepetsa ndalama zopangira popanda kukhazikika, ndipo nthawi zina zimakhala zowonjezera pakuwongolera kwabwino.

⚙️ Mphamvu - Ogwira ntchito, yoloza akupanga akupanga njira zothetsera R & D ndi kupanga

Makina amakono akupanga amapereka mphamvu zambiri poyerekeza ndi makina ambiri - Shear osakaniza ndi otayika - kukakamiza homogenizer. Mphamvu imaperekedwa mwachindunji m'madzi kudzera mu sonotrode, kuchepetsa zotayika ndikuthandizira nthawi yochepa. Mndandanda womwewo ndi wofanana ndi mavoti a labotale ku mafakitale opanga mafakitale, kusinthasintha kosavuta.

Ndi makina oyenerera a dongosolo, ma cavitatititikhala amatha kupezekanso kuchokera ku mamilili, ndikuwonetsetsa kuti ntchito yodalirika ikhale yodalirika.

1. Kutsatsa kwa labotale ndi kolondola

Mu R & D malo okhala, benctop akupanga homogenizer amalola kuwunika mwachangu kwa mapangidwe ndi magwiridwe antchito. Ofufuzawo amatha kusintha mawonekedwe, ma pulse mode ndi kukonza nthawi yodziwiratu kwa kukula kwa magwero, polyducation ndi bata.

• Zoyenera kwa ochepa - mawonekedwe a batch
• Imathandizira kapangidwe ka zoyeserera (Doe) njira
• Kuthamanga kwa nthawi yayitali
• Sinthani pagawo la paramu ku Pilot - Zida zazikulu

2. Scaam yopanda pake - Mpaka woyendetsa ndege ndi kupanga kwathunthu

Makina opanga mafakitale amagwiritsa ntchito ma cell am'manja ndi sonotrodes angapo kuti azitsatira mitsinje yopitilira kapena ma batchi akulu. Poyerekeza ndi mphamvu ndi nthawi yokhazikika kuchokera ku labu kuti ibzale, sikelo - mmwamba zimakhala zowongoka ndikulosera, kuchepetsa chiopsezo chosayembekezereka pazopanga.

3. Mphamvu ndi kukonza ma vs. njira zachikhalidwe

Akupanga emulsization amagwira ntchito kunsidwe kotsika kwambiri ndi mphamvu zambiri komanso zovuta zamakina kuposa okwera - ma homogenizer. Pali zigawo zosasunthika, zopanda zisindikizo - Zisindikizo zotsika komanso kuvala kochepa, zomwe zimapangitsa kuti zikhale nthawi yotsika ndi kukonza pa nthawi yanthawi yayitali.

• Kuvala kwamakina ochepera poyerekeza ndi ma stator
• Zophatikizika zophatikizika
• Mphamvu zimayang'ana komwe zimafunikira
• Mawonekedwe a mawonekedwe ophatikizidwa mu mizere yomwe ilipo

🏭 Chifukwa chiyani labotaries ndi opanga amasankha Hanspire akupanga makina okhazikika a emulsions

Zida za hanspire akupanga zimapangidwa kuti zizifuna zodzikongoletsera komanso zamankhwala, kuphatikiza njira, kukhazikika komanso kukhazikika. Ndi mitundu yodzipereka yofufuza kwa labotale ndi kupanga mafakitale, makina a Hanspire amathandizira opanga ophatikizika, motalika - emulsions osatha ndi ma nanoemulsions ndi mphamvu yolimba.

Kuchokera pamagulu a bonatani a Nano - Makina ophatikizika, njirazi zimathandizira kugwiritsa ntchito mosiyanasiyana pokumana ndi miyezo yapamwamba yodalirika, ukhondo ndi kukonza zobwereza.

1. Njira zothetsera zokongoletsera za zodzikongoletsera ndi zamankhwala

AKukhazikika kwambiri 20khz mafakitale akupanga homogenizer yazitsamba zamankhwala zamankhwala zamankhwala ndikupanga - emulsizationlapangidwa kuti azitha kusamalira ma viste cosmetic ndi zitsamba zotsatsa. Ntchito yake yokhazikika 20 khz ndi chimphepo champhamvu chothandizira odalirika a nanoemilsion, kukulitsa gawo logwira ntchito ndi kukhazikika kwa emulsion.

• Zabwino kwa zodzikongoletsera zachilengedwe ndi dermo - zodzikongoletsera
• Imathandizira Ethanol / Madzi ndi Mafuta - Kutulutsa
• Kutulutsa mabatani owonjezera
• Oyenerera ndi ma batch

2. Sonochemistry sonochest ndi R & D kuthekera

Pa labotale - chitukuko chaLaborator akuyenda bwino sonochemin 20khz akupanga homogenizer pobalalitsa kuyesa kwa kuchotsaamapereka ulamuliro wapadera komanso wosinthasintha. Zimathandizira kuwunika mwachangu kwa emulsifiers, mapangidwe a mafuta ndi machitidwe, kuchirikiza koyambirira kwa koyambirira - mawonekedwe a siteji ndi kufufuza kafukufuku wa sonochemist.

3. Kukhazikika kwa mafakitale, kusinthika komanso kotalika - makampani opanga mafakitale

Makampani ogulitsa Hanspire - Makina opanga akupanga amatsimikiziridwa mu ntchito zovuta kuchokera ku zitsulo zochokera ku zitsulo zimasungunuka kwa nanomatadium, kuwonetsa ukadaulo wamphamvu komanso kulimba. AKuchita bwino kwambiri kwa 20khz mafakitale akupanga chitsulo kusungunuka ku chithandizo chamadzimadzi alunumndiKukhazikika kwamphamvu akupanga homogenizer kwa nano graphene kufalitsa ndi CBDSonyezani kuthekera kwawo kwamphamvu - kufunafuna malo, kumasulira kukhala kodalirika - magwiridwe antchito odzikongoletsa ndi mankhwala.

• Kulemera - Kugwira ntchito kwa 24/7
• Katswiri ku Nano - Kubala ndi Mafuta Ovuta
• Zopangidwa chifukwa choyeretsedwa molunjika ndi kuphatikiza
• Scalable Plafforms ikugwira mafakitale angapo

Mapeto

Akupanga emulsization wakhala ukadaulo wofunikira kuti ukhale wokhazikika, wokwera - emulsions ogwiritsira ntchito ndi ma nanoemulsions muzodzola komanso mankhwala. Mwa kukonzekera patali, opanga amatha kupanga mawilo abwino, yunifolomu yomwe imathandizira kulimbitsa thupi, malingaliro a sewero komanso ntchito yogwira ntchito wamba poyerekeza ndi njira wamba.

Kwa zinthu zodzikongoletsera, ultrasound imatanthawuza mawonekedwe osalala, mayamwidwe apamwamba kwambiri komanso mawonekedwe okhazikika omwe amapindika. Mu mankhwala opangira mankhwala, zimathandizira kukulitsa bioaavailabilobility kwa zinthu zosasunthika, kuteteza chitetezo cha zinthu zowoneka bwino komanso dosing. Izi zabwino zimatheka ngakhale nthawi zambiri zimachepetsa kuchuluka kwazinthu zambiri, zomwe zimayambitsa zilembo zoyeretsa komanso zoopsa zotsika.

Mphamvu - Makina othandiza akupanga mosavuta kuchokera ku labu kuti abzale, chitukuko chosavuta ndi kusamutsa ukadaulo. Chida cha Hanspire cha Akupanga chimapereka chodalirika, okhazikika - Mayankho okhazikika pofuna kukakamiza zodzikongoletsera komanso mankhwala, zomwe zimapangitsa njira zopangidwa ndi zinthu zopangidwa ndi zinthu zauzimu.

Mafunso omwe amafunsidwa kawirikawiri ponena za akupanga emulsion

1. Kodi akupanga emulsization?

Akupanga emulsization ndi njira yomwe imagwiritsa ntchito kwambiri - mafunde akomwe amatulutsa pafupipafupi kuti apange pachakudya. Zotsatira za microbububle zimagwera ndikupanga mphamvu zowoneka bwino zomwe zimaswa mabelo akuluakulu kukhala ocheperako, ndikupanga emulsions yabwino kapena nanoemulsions ndi kukhazikika kwamphamvu ndi magwiridwe antchito.

2. Kodi akupanga emulsization amasiyana bwanji ndi mkulu - Kusakanikirana?

Wokwera - Zojambula za Shear amadalira zamatsenga ndi zotupa zambiri, pomwe akupanga makina amapanga cavitation yokhala ndi microscopic mulingo wa microscopic. Izi zimathandiza kuti ultrasound kuti mukwaniritse kukula kwa magwero, kugawa kocheperako ndipo nthawi zambiri kumakhala kokhazikika pamawu otsika kwambiri.

3.

Inde. Ngakhale ma ultrasound amapanga kutentha, nthawi zowonekera ndizochepa ndipo imatha kulamulidwa ndi makina ozizira ndi mitundu yozizira. Mapangidwe ambiri okhala ndi kutentha - mavitamini owoneka bwino, ma enzyme ndi mabotolo azomwe amakonzedwa bwino pogwiritsa ntchito ma akupanga zinthu mosamala.

4. Kodi kukula kwa magwero kuti chikwaniritsidwe ndi ma systic?

Maulalo akupanga zida mwamphamvu amapanga madontho a submicron ndi nanoemulsions, nthawi zambiri m'ma 50-200 nm kutengera kapangidwe kake ndikuwongolera magawo. Kukula kopambana kumatengera zinthu monga gawo lamafuta kuphatikizika, maofesi ocutant, mphamvu zamagetsi ndi kukonza nthawi.

5.

Inde. Makina opanga mafakitale amagwiritsa ntchito ma cell a ma cell ndi makanema ambiri amapangidwira kupitirira kapena lalikulu - mabatani. Poyerekeza ndi mphamvu ya mphamvu ndi nthawi yokhazikika kuchokera ku labu - Mayesero a Scale, Opanga amathanso mpaka matiniwo kapena masauzande a malita pomwe akusungabe kukula komanso kukhazikika.