Ultrasonic homogenizer is widely used

Ultrasonic homogenization technology is mainly used for the preparation and production of laboratory samples, including the homogenization, emulsification, suspension of various substances, as well as the acceleration of chemical reactions, cell fragmentation and the extraction of cell inclusions. The use of ultrasonic homogenization equipment can selectively destroy certain substances, streamline the cumbersome liquid preparation process, and increase the yield of many reactions.

Ultrasonic homogenization
Ultrasonic homogenizers can work with greater efficiency than mechanical processing equipment such as planetary ball mills, rotors or gap homogenizers, especially enabling experimental results that require a large number of repeated cycles. The use of ultrasonic homogenizers has become critical, where even the smallest sample volumes can be processed quickly, cost-effectively and repeatably.
Destroys cells and microbes
In modern laboratories, ultrasonic homogenizers are used to break down cell walls to extract cell contents without damaging those cell contents. The purpose of cell decomposition or lysis is to destroy part of the cell wall or the entire cell to release biomolecules. The so-called lysates may include, for example, plasmids, receptor assays, proteins, DNA, RNA, etc. The steps of cleavage are separation, organelle separation and protein extraction and purification. The extracted substance (lysate) must be separated and needs to be further studied or applied, for example for proteomics studies. Ultrasonic homogenizer is a common tool for successful cell lysis.
The destruction of the cell membrane depends largely on the elasticity of the cell. By varying the input ultrasound energy and extraction power, cellular components, such as mitochondria or cytoplasm, can be partially destroyed. For particularly resistant bacteria (e.g., streptococcus), fungi, spores, yeasts, or tissue samples, direct destruction with very high ultrasonic amplitudes can be achieved by microtips, as very large energy inputs can be achieved in minimal sample volumes.
Applications in biochemistry and medicine
Destructive tissue culture
Subcellular components and viruses are destroyed without any damage.
Paternity test
Urology department
Biochemical membrane analysis of sperm components
Gene study
Extracting DNA from human material.
Liposome preparation
The treatment of smallpox vaccine
Prepare a uniformly distributed infection solution
Ultrasonic dispersion
Using ultrasonic energy, solid particles or even liquids can be dispersed into another carrier. Nano-scale powders such as titanium dioxide or pyrolytic silica are increasingly used in the production of test coatings and varnishes or for polishing small body surfaces due to their large specific surface area and increased reaction potential.

Ultrasonic graphene dispersion
In addition, these substances have a negative tendency to agglomerate, with poorer mobility and wettability as a result. The formed agglomerates are destroyed by means of an ultrasonic homogenizer and the dispersion is permanently stabilized to prevent re-agglomerations.
Ultrasonic emulsification
When phacoemulsification is used, two immiscible liquids, such as oil and water, are processed into a quasi-homogeneous emulsion. Finely dispersed emulsions with very small droplet sizes and very high stability can be produced with the help of ultrasonic homogenization techniques compared to conventional methods using, for example, rotors. The resulting emulsion does not form clumps or precipitate droplets. For conventional methods, such as rotors or stirrers, slow stirring usually causes the liquid to separate. Too fast stirring will lead to air, dust and other debris in the emulsion. Ultrasonic homogenizers can often be used in pharmacies for high-quality, small-scale ointment production.

Ultrasonic emulsification
Ultrasonic homogenization
Ultrasonic homogeneous lotions come in many different forms in everyday life, such as in cosmetics or lotions. Technical applications for ultrasonic homogenization range from the production of paints and varnishes to the homogenization of wastewater and soil samples (for analytical purposes) to sample preparation for particle size analysis.
In particular, it is necessary to continuously check the presence of heavy metals, fats or oils in industrial wastewater in environmental laboratories so that immediate measures can be taken when the concentration exceeds the standard. In order to obtain representative analytical results, it is necessary to transform the wastewater sample into a homogeneous state. These need to be achieved by ultrasonic homogenization in a short time with high reliability.
In agriculture, ultrasonic homogenizers are used for sample preparation. For example, the ultrasonic homogenizer performs intensive and fine homogenization of rose cells in a very short period of time. The resulting particle size is less than 1μm, which simplifies subsequent filtration to wash out ions because no clumps are formed.
Post time: 2024-01-02 05:29:18